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Table 4 Associations with low-, moderate- and high-risk hs-CRP levels

From: Abdominal obesity in type 1 diabetes associated with gender, cardiovascular risk factors and complications, and difficulties achieving treatment targets: a cross sectional study at a secondary care diabetes clinic

  

Hs-CRP risk levels

All (With CRP)

Low (<  1 mg/l)

Moderate (1 to ≤3 mg/l)

High (> 3.0 to ≤ 8.9 mg/l)

 

Increasing hs-CRP risk levels

N = 171

N = 107

N = 44

N = 20

 

N = 171

N (%) or median (q1, q3)

P a

COR (CI)

P b

AOR (CI)

P b

Gender

Women

66 (39)

35 (33)

19 (43)

12 (60)

0.017

2.0 (1.1–3.8)

0.023

–

NS

Men

105 (61)

72 (67)

25 (57)

8 (40)

Age

42 (30, 50)

42 (31, 50)

40 (27, 51)

42 (29, 53)

0.73 c

1.00 (0.97–1.02)

0.72

–

NS

Abdominal obesity

22 (13)

7 (6)

5 (11)

10 (50)

< 0.001

7.0 (2.8–17.9)

< 0.001

5.3 (2.1–13.6)

< 0.001

HbA1c > 70 mmol/mol

51 (30)

27 (25)

11 (25)

13 (65)

0.004

2.2 (1.2–4.3)

0.016

–

NS

TC (mmol/l)

4.6 (4.1, 5.2)

4.5 (4.0, 5.1)

4.8 (4.1, 5.4)

4.8 (4.4, 6.0)

0.035 c

1.5 (1.2–2.0)

0.002

–

NS

Triglycerides (mmol/l)

0.9 (0.7, 5.2)

0.8 (0.6, 1.1)

1.0 (0.7, 1.4)

1.3 (0.9, 2.4)

< 0.001 c

3.2 (1.9–5.7)

< 0.001

2.82 (1.68–4.93)

< 0.001

HDL (mmol/l)

1.5 (1.3, 1.8)

1.6 (1.3, 1.8)

1.6 (1.3, 1.7)

1.4 (1.1, 1.7)

0.32 c

0.6 (0.2–1.4)

0.21

–

NS

LDL (mmol/l)

2.9 (2.3, 3.3)

2.7 (2.2, 3.2)

2.9 (2.4, 3.6)

3.2 (2.8, 3.6)

0.010 c

1.7 (1.2–2.4)

0.002

–

NS

SBP (mm Hg)

120 (115, 130)

120 (115, 130)

120 (110, 130)

128 (120, 134)

0.16 c

1.02 (0.99–1.05)

0.15

–

NS

DBP (mm Hg)

70 (70, 75)

70 (65, 75)

70 (66, 80)

75 (70, 78)

0.036 c

1.07 (1.02–1.12)

0.003

–

NS

LLD

82 (48)

50 (47)

21 (48)

11 (55)

0.55

1.2 (0.6–2.2)

0,60

–

NS

AHD

51 (30)

31 (29)

14 (32)

6 (30)

0.82

1.1 (0.6–2.1)

0.78

–

NS

Smoking d

18 (10)

11 (10)

5 (12)

2 (10)

0.96

–

–

–

–

Physical inactivity e

22 (13)

10 (10)

10 (23)

2 (10)

0.28

–

–

–

–

CV complications

7 (4)

4 (4)

0

3 (15)

0.16

2.3 (0.4–12.1)

0.30

–

NS

  1. NS Non-significant
  2. a Linear-by-linear Association (Exact 2-sided) unless indicated. b Ordinal regression analyses. c Kruskal-Wallis test. Missing values: d n = 2; e n = 3. d, e Not included in the ordinal regression analyses