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Table 2 Genes differentially expressed in tumors from normal-weight compared to obese women. Genes in bold remained statistically significant when age at diagnosis and self-described ethnicity were included with BMI in ANOVA

From: Effect of obesity on molecular characteristics of invasive breast tumors: gene expression analysis in a large cohort of female patients

  

All BMI groupsa

Normal-weight vs obese

Gene Symbol

Probe

P-value

P-value

Fold-change (normal-weight/obese)

ABCA3

204343_at

4.5E-05

9.8E-06

0.66

ACSL1

201963_at

0.0001

3.0E-05

1.48

APOD

201525_at

0.0002

2.3E-05

2.36

AVL9

212471_at

4.9E-05

9.7E-06

0.82

BUB1

209642_at

1.6E-05

6.5E-05

0.64

CCNB2

202705_at

2.8E-05

1.4E-05

0.64

CDC25C

205167_s_at

0.0002

7.4E-05

0.67

CDC6

203968_s_at

0.0002

8.5E-05

0.72

CENPA

204962_s_at

8.9E-05

3.2E-05

0.59

CENPF

207828_s_at

2.3E-05

6.7E-05

0.65

CEP55

218542_at

7.6E-05

5.1E-05

0.60

CHEK1

205394_at

0.0002

5.1E-05

0.70

CORO2B

209789_at

0.0002

3.9E-05

1.27

DENND1A

219763_at

3.3E-07

5.0E-08

0.66

EXO1

204603_at

0.0003

8.8E-05

0.80

EZH2

203358_s_at

3.2E-05

1.5E-05

0.68

FLRT2

204359_at

0.0005

8.6E-05

1.60

FOXM1

202580_x_at

1.2E-05

8.9E-06

0.67

GTSE1

204317_at

0.0003

7.7E-05

0.83

IGF1

209542_x_at

2.4E-05

6.2E-06

1.75

211577_s_at

3.5E-05

1.0E-06

1.72

KIF14

206364_at

1.5E-05

1.0E-05

0.70

KIF18B

222039_at

9.1E-06

1.1E-05

0.67

KIF2C

209408_at

0.0002

3.0E-05

0.66

KIF4A

218355_at

0.0001

5.5E-05

0.64

KLHL12

219931_s_at

0.0005

8.4E-05

0.79

MELK

204825_at

4.0E-06

2.2E-06

0.58

MKI67

212022_s_at

0.0007

3.5E-05

0.69

212021_s_at

0.0002

3.4E-05

0.71

NUDT13

214136_at

0.0005

9.3E-05

0.74

OGN

218730_s_at

0.0003

5.4E-05

2.05

OIP5

213599_at

7.5E-05

4.5E-05

0.67

PARP1

208644_at

0.0004

6.7E-05

0.81

PDIA4

211048_s_at

0.0005

9.5E-05

0.80

PRC1

218009_s_at

0.0002

7.3E-05

0.66

PSMD4

200882_s_at

0.0005

9.1E-05

0.83

RBMS3

206767_at

0.0003

5.9E-05

1.28

SCCPDH

201826_s_at

0.0005

9.8E-05

0.73

SERPINB13

216258_s_at

3.9E-05

2.6E-05

0.93

TADA2A

209938_at

0.0005

9.1E-05

0.84

TIMELESS

203046_s_at

1.1E-05

1.5E-05

0.75

TYMS

202589_at

6.5E-06

3.9E-06

0.65

WHSC1

209054_s_at

0.0003

8.6E-05

0.81

ZWINT

204026_s_at

8.6E-06

3.1E-06

0.67

  1. aGenes that differed significantly in expression levels when ANOVA was performed across normal weight, overweight and obese groups