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Figure 5 | BMC Obesity

Figure 5

From: Altered NK cell function in obese healthy humans

Figure 5

Effect of leptin stimulation on cell proliferation of human NK cells. PBMCs from healthy normal weight and obese subjects were stimulated with 50 nM human recombinant leptin or vehicle for 7 days, stained with antibodies and analyzed with flow cytometry. (A) Representative histograms of CSFE staining showing four proliferation peaks of NK cells from a normal weight (upper histogram) and an obese (lower histogram) subjects. The peaks, from P4 (parental generation) to P1, represent successive generations. (B) Numbers of proliferating NK cells as percentage of NK cells. Data are expressed as mean + SEM.

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